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Data Upload and Annotation

EcoToxXplorer accepts processed multiple dose expression matrix data matrix as input. There is a standard format which needs to be followed - hover your mouse to the question mark next to Data File for more details.

MDMB (large transcriptomic response)
This part of a larger transcriptomic dose-response study by EPA using 6 chemicals, 4 time points, and 6 dose groups (including control). (DOI 10.1007/s00204-016-1886-5)
Chemical: 4,4'-Methylenebis(N,N-dimethyl) benzenamine (CAS number: 101-61-1). Doses: 50, 200, 375, 500, and 750 ppm. Tissue: Thyroid. Organism Rattus norvegicus (F344 rats). Sex: Female. Duration: 2 weeks.
Bromobenzene (moderate transcriptomic response)
This part of a larger transcriptomic dose-response study by EPA using 6 chemicals, 4 time points, and 6 dose groups (including control). (DOI 10.1007/s00204-016-1886-5)
Chemical: Bromobenzene (CAS number: 108-86-1). Doses: 25, 100, 200, 300, and 400 mkd. Tissue: Liver. Organism Rattus norvegicus (F344 rats). Sex: Male. Duration: 2 weeks.
Hydrazobenzene (low transcriptomic response)
This part of a larger transcriptomic dose-response study by EPA using 6 chemicals, 4 time points, and 6 dose groups (including control). (DOI 10.1007/s00204-016-1886-5)
Chemical: Hydrazobenzene (CAS number: 122-66-7). Doses: 5, 20, 80, 200, and 300 ppm. Tissue: Liver. Organism Rattus norvegicus (F344 rats). Sex: Male. Duration: 2 weeks.
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